Glutathione for Skin Brightening and Anti Aging in Cosmetic Formulations Glutathione vs. Tranexamic Acid for Melasma: Which Works Better? Collagen and glutathione supplements are a synergistic anti aging, skin lightening, and wellness formula. They combine collagen (often marine derived) to improve skin elasticity, hydration, and reduce wrinkles with glutathionea potent antioxidant that The Glutathione Derivative, GSH Monoethyl Ester, May Effectively Whiten Skin but GSH Does Not